PHARMACOLOGY

Stainless steel 304 guinea pig cage for animal housing system for various types of pharmaceutical laboratories.

Stainless Steel 316L offers excepti> The tags are designed with the well-being of small animals in mind, featuring smooth edges and a lightweight c> The tags are easy to attach and secure, making the process quick and stress-free for both the animals and the handlers. Each tag is uniquely identifiable, allowing for precise tracking and management of laboratory animals, which is crucial for research accuracy. We also offer customized numbering to meet specific user requirements, ensuring that each tag perfectly fits the unique needs of your research.Our Animal dentity Tag System provides an indispensable tool for researchers, combining practicality with animal welfare. Choose our tags for a dependable and humane solution to animal identification.

The Light and Dark Test, also known as the Light-Dark Box Test, is a behavioral assay used in pharmaceutical research to assess anxiety-like behaviors in rodents, specifically rats and mice. Here is how it is used and its significance in research: Assessment of Anxiety: The primary purpose of the Light and Dark Test is to evaluate anxiety-like behaviors in rodents. The test is based on the natural aversion of rodents to brightly lit areas and their preference for dark, enclosed spaces. This preference is linked to their instinct to avoid potential predators and open spaces. Test Setup: The apparatus typically consists of a box divided into two compartments: one brightly lit (light compartment) and the other dark (dark compartment). The light compartment is usually open and illuminated with bright light, while the dark compartment is enclosed and covered, providing a shaded area. Behavioral Measures: During the test, a rodent is placed in the middle of the apparatus, and its behavior is observed and recorded. Key behavioral measures include: Latency to Enter the Dark Compartment: The time taken for the rodent to enter the dark compartment from the light compartment. Time Spent in Each Compartment: The amount of time the rodent spends in the light compartment versus the dark compartment. Number of Transitions: The number of times the rodent moves between the light and dark compartments. Anxiolytic and Anxiogenic Drug Testing: The Light and Dark Test is commonly used to evaluate the effects of anxiolytic (anxiety-reducing) and anxiogenic (anxiety-inducing) compounds. Anxiolytic drugs typically increase the time spent in the light compartment and the number of transitions between compartments, indicating reduced anxiety. Conversely, anxiogenic substances reduce the time spent in the light compartment and the number of transitions. Studying Genetic and Environmental Factors: Researchers use the Light and Dark Test to study the impact of genetic modifications, environmental factors, and stress on anxiety-like behaviors. Comparing the behavior of genetically modified rodents with wild-type controls, or assessing the effects of environmental stressors, can provide insights into the biological and environmental determinants of anxiety. Behavioral Phenotyping: The test is part of a broader battery of behavioral assays used for phenotyping rodent models. It provides valuable data on anxiety-related behaviors, contributing to a comprehensive understanding of the behavioral phenotype of different strains or genetically engineered models. Mechanistic Studies: The Light and Dark Test can be used in combination with pharmacological interventions to investigate the underlying mechanisms of anxiety. By examining the effects of drugs that target specific neurotransmitter systems (e.g., serotonin, GABA), researchers can gain insights into the neurobiological pathways involved in anxiety. Validation of Animal Models: The test is used to validate animal models of anxiety disorders. By demonstrating that certain genetic, pharmacological, or environmental manipulations lead to anxiety-like behaviors in the Light and Dark Test, researchers can establish the relevance of these models for studying human anxiety conditions.

The animal is placed on the rotating lane of the Rota Rod and the timer is started. When the animal drops safely into its own lane, the time latency to fall (minutes and seconds) and rotation speed are automatically recorded. A removable upper separator for rat models is included to prevent interference between animals running in adjacent lanes. The Rota Rod is controlled by an advanced microprocessor which provides precise timing control and ultra-accurate speed regulation. Rotation can be electronically set at a constant speed (4-40 rpm). Alternatively, acceleration rate may be selected at a defined time (30 sec to 10 min, 1 sec increments). Acquired data is saved in table form by lanes/trials. Now even easier to use! The new touchscreen graphic user interface allows clear visualization of timing and speed for each lane. Change modes, adjust speed, and create protocols right from the main screen for greater flexibility with maximum functionality and usability.

MILTON ENTERPRISES Introduces Advanced Digital Grip Strength Meter to Measure grip Strength of fore limbs & hind limbs of Rat & Mice to Observe effects of Drugs, Toxic Agents, Muscle Relaxants Disease,Digital Grip Strength Meter to Measure grip Strength of fore limbs & hind limbs of Rat & Mice to Observe effects of Drugs, Toxic Agents, Muscle Relaxants Disease Ageing Factor Neural Damages on Muscle Strength.MILTON ENTERPRISES provides DIGITAL GRIP STRENGTH METER along with T- shape, mesh & Trianle shape attachments which is made by stainless steel 304. In addition to battery back up acility miltom enterprises provides software utility to store data & retrive it when ever its required for examine.

A Rotary Flask Shaker is a laboratory instrument designed for mixing and agitation of liquid samples in glassware, typically flasks, using orbital or reciprocal motion. Here's a concise overview: - **Purpose**: Used for various applications including culturing, mixing, and extraction processes in biological, chemical, and pharmaceutical laboratories. - **Features**: Equipped with adjustable speed controls, timers, and sometimes temperature controls to optimize mixing conditions for different types of samples. - **Types**: Available in different sizes and capacities to accommodate various flask sizes and sample volumes. - **Applications**: Widely used in microbiology for bacterial and yeast culture growth, in chemistry for chemical reactions requiring agitation, and in pharmaceutical labs for drug formulation and testing. - **Importance**: Essential for achieving uniform mixing and efficient oxygen transfer in liquid cultures, which is crucial for maintaining cell viability and maximizing yields in biotechnological processes. In summary, Rotary Flask Shakers are indispensable tools in laboratory settings where precise agitation and mixing of liquid samples in flasks are required for research, development, and production purposes.

Polyprelene cage, polycarbonate cages for rat & mice, for pharmaceutical animal housing system.

Stainless steel racks for rat & mice cages, which requires various types of animal housing system in pharmaceutical laboratories.

The Elevated Plus Maze (EPM) is a widely used behavioral test in pharmacology and neuroscience research to assess anxiety-related behaviors in rodents, typically mice or rats. Here's how it is used and its significance: Assessment of Anxiety: The primary use of the EPM is to evaluate anxiety levels in rodents. The maze consists of two open arms and two closed arms, elevated above the ground. Rodents naturally prefer enclosed spaces and avoid open, elevated areas due to fear of falling and exposure. Thus, the time spent in the open arms versus the closed arms serves as an indicator of anxiety levels. Testing Anxiolytic and Anxiogenic Compounds: The EPM is used to screen the effects of pharmacological agents on anxiety. Anxiolytic (anxiety-reducing) drugs typically increase the time rodents spend in the open arms, indicating reduced anxiety. Conversely, anxiogenic (anxiety-inducing) substances reduce the time spent in open arms. Behavioral Profiling: The EPM helps in profiling the behavioral effects of various compounds. Researchers can observe changes in exploratory behavior, risk assessment, and overall activity levels, which provide insights into the drug's impact on anxiety and related behaviors. Mechanistic Studies: By using the EPM in conjunction with pharmacological manipulations (e.g., using receptor antagonists or agonists), researchers can investigate the underlying mechanisms of anxiety and the role of specific neurotransmitter systems, such as serotonin, GABA, and glutamate. Genetic Research: The EPM is used to study the genetic basis of anxiety by comparing the behavior of different rodent strains or genetically modified animals. This can help identify genetic factors that influence anxiety and contribute to our understanding of anxiety disorders. Longitudinal Studies: Researchers use the EPM to conduct longitudinal studies on the effects of chronic drug treatment, stress, or developmental changes on anxiety. This helps in understanding how these factors influence anxiety over time. Validation of Animal Models: The EPM is an essential tool for validating animal models of anxiety disorders. By showing that certain genetic, environmental, or pharmacological manipulations lead to anxiety-like behaviors in the EPM, researchers can establish the relevance of these models to human anxiety conditions. Behavioral Phenotyping: The EPM is part of a battery of behavioral tests used for phenotyping rodent models, particularly in studies investigating the impact of neurological or psychiatric conditions. It provides valuable data on how these conditions affect anxiety-related

Milton Enterprises introduces Eddyâ??s hot plate (Analgesiometer) is used to study of analgesic property of pharmaceutical substance in pharmacy colleges, medical colleges, research institutes and We are experts in the supply and manufacture of Video Tracking System required for monitoring the laboratories and research organisms. Our system can track and detect even the minute changes in the position and transfer the readings to the special software provided with the system. The software can draw graphs or compare various parameters which can be easily selected from the software. The high resolution of the camera enables the researchers to monitor the behavior remotely. Details Video Tracking System for all Types of Mazes : Video tracking system is useful in the study of laboratory behavior, such as to screen Grooming, Rearing, Self biting, Try to escape, Time spending in specific region, travel distance, No of visits, Etc... all these parameters are study in behavior study, with Elevated Plus maze, Y maze, T-maze, 8 arm radial maze, water maze, tail suspension test, Forced swimming test, open field. Apparatus : VIDEO TRACKING System for all Mazes : for Force swimming test, Tail Suspension Test, plus Maze, Y- Maze, T- Maze, Zero Maze, Water Maze, Open Field Maze, Video Tracking System is to used to screen Travel Distance, Time Spend in Specific Region, Number of Visit, Exploration, Rearing, Grooming, Mobility, Immobility, Strong Mobility, Try to Escape. All these parameter we canâ??t screen accurately by giving personal presence, so first record the video of the particular maze & play that video in the Video tracking system& screen so many parameter & Data is automatically exported for statistical analysis in excel as above & more than that as you desired. From following mazes as, Intex wired camera (14 Megapixels) Including Video Tracking System. Optional : Mazes are made by non reflective material & FRP. Mazes : Force Swimming Test Apparatus for Tail Suspension Test Apparatus Elevated plus maze for mice Elevated plus maze for rat Y maze for mice Y maze for rat T maze for mice T maze for rat Zero maze for mice Zero maze for rat Water maze for mice (made of FRP)* Water maze for rat (made of FRP)* Multiple unit open field enclosure Radial arm maze for mice (8 arm) Radial arm maze for rat (8 arm) pharmaceutical industries, especially in pharmacology departments, LEâ??s Analgesiometer having digital Timer, with 999.99 seconds resolution, & digital temperature controller having resolution 0.1?C, with temperature range as ambient to 65?C pedal switch needed to save readings, no holder has been change for rat and mice. Key Features : Timer: Digital. Temperature controller & indicator: Digital. Temperature Range: Ambient to 65?C. Temperature accuracy: +/- 0.1?C. Animal Chamber: Transparent, Easy to Clean. Pedal Switch: to freeze reading.

An Animal Cage Change Station is a specialized laboratory device designed to ensure a clean, safe, and efficient environment for changing animal cages. It features a work surface made of antimicrobial materials, HEPA filtration for contaminant-free air, and laminar airflow to prevent airborne contamination. The station includes bright LED lighting, enclosed workspace with glove ports, integrated waste disposal systems, and adjustable components for ergonomic use. Its ventilation system removes contaminated air, while storage options keep tools and supplies organized. This station enhances hygiene, productivity, and safety in research and vivarium settings.